2021

1. 11th International Ceramide Conference  19 - 22 April 2021 (VIRTUAL), 

Petra Grbčić, Thomas Eichmann, Sandra Kraljević Pavelić, Mirela Sedić 

Altered sphingosine-1-phosphate/ceramide balance contributes to the development of resistance to vemurafenib in BRAFV600E mutant colon cancer cells 

 

2. EACR 2021 Congress, Innovative Cancer Science: Better Outcomes through Research held virtually from 09 - 12 June 2021 

M. Sedić*, I. Car*, A. Dittmann, O. Vasieva, P. Grbčić, M. Klobučar, S. Kraljević Pavelić. (* equal contribution)

Integrated proteomics and bioinformatics approach reveals caveolae-associated signalling as novel druggable vulnerability of vemurafenib-resistant colon cancer cells with BRAFV600E mutation  - poster presentation

 

3. 2nd International Conference on Cell and Experimental Biology (CEB-2021) JULY 12-14, 2021 | VIRTUAL; invited talk

M. Sedić

"Proteomic Profiling of BRAFV600E Mutant Colon Cancer Cells Reveals the Role of Nucleophosmin in Mediating the Resistance to BRAF Inhibition by Vemurafenib"

 

 

2019

 1. CEOC 2019, 15th Central European Oncology Congress,  Opatija, Croatia

Petra Grbčić, Sandra Kraljević Pavelić, Mirela Sedić 

Differences in molecular and cellular characteristics between BRAF V600E-mutated vemurafenib resistant and sensitive colon cancer cell lines

 

Iris Car, Marko Klobučar, Sandra Kraljević Pavelić, Mirela Sedić 

Proteomic profiling of BRAF V600E mutant colon cancer cells with acquired resistance to vemurafenib

 

2. 13th Mass Spectrometry School in Biotechnology and Medicine (MSBM) - Dubrovnik, Croatia

Iris Car, Marko Klobučar, Sandra Kraljević Pavelić, Mirela Sedić 

Optimization of protocol for secretome collection from vemurafenib-resistant BRAFV600E mutant colon cancer cells for mass spectrometry-based proteome analysis

 

3. 13th European Summer School on Advanced Proteomics, FEBS 2019 Advanced Course, Varna, Italy

Petra Grbčić, Marko Klobučar, Tania Gamberi, Sandra Kraljević Pavelić, Veronika Horvat, Mirela Sedić

Proteomic signatures associated with BRAF V600E mutation in colorectal cancer

 

4. International Doctoral Conference, AARC, University of Rijeka, Croatia

Iris Car, Marko Klobučar, Sandra Kraljević Pavelić, Mirela Sedić 

Secretome analysis of BRAF V600E-mutant colon cancer cells with acquired resistance to vemurafenib

 

Petra Grbčić, Sandra Kraljević Pavelić, Mirela Sedić 

Sphingolipid metabolism is dysregulated in BRAF V600E mutant colon cancer cells resistant to vemurafenib